In spite of our best efforts, spills happen and are a part of any laboratory work or course. If you have a spill and it is too large to handle or is too hazardous, how are you supposed to respond? A quick response by laboratory personnel to a spilled chemical, whether it is a minor or major spill, may limit the consequences of the spill. This training explains your role during spill response and provides guidelines to follow in case of minor or major spill.